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Bioactive Materials

ReportTime:2018-8-24 16:07:53Views:
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I. BIOMEDICAL GRADE HYDROXYAPATITE

1. Product Description

Hydroxyapatite (HA) is the main inorganic mineral component of animal and human skeleton, which has good biological activity and biocompatibility. HA is a synthetic material similar to the main inorganic components of natural bone. It can form a close combination with bone. It is non-toxic, non-irritating, non-allergic, non-mutagenic, non-hemolytic, non-destructive to biological tissues, and can form a strong chemical combination with bone. It is easy to shape and is widely used in bone tissue restoration. The product specifications meet the requirements of GMP standard of the medicine of China, YY0303-1998 Medical Hydroxyapatite Powder.

2. Physicochemical Properties

Chemical name: hydroxyapatite
Molecular weight: 1004
Molecular formula: Ca10(PO4)6(OH)2
Density: 3.16g/cm3
Melting point: 1650 ℃
Element content: purity ≥ 99%, heavy metal ≤ 4 ppm, arsenic ≤ 1 ppm
Whiteness: 96
PH: 7.4
Average Size: 300nm~20μm in various specifications
Morphology: amorphous form, sphericity, fibrous form
Cytotoxicity test: relative survival rate of 100% extract group ≥ 90%

3. Application Range

This product can be used to make HA bioceramics, coatings and composite materials. After sterilization, it can also be used for plastic and cosmetic surgery, dental surgery, repairing bone defects and bone fusion caused by trauma, tumors, inflammation, bone diseases, etc. This product can be mixed with other bioceramic materials, such as β-TCP, CSI and other powders to make composite bioceramic scaffolds with different compositions by 3D printing.




II. BIOMEDICAL GRADE β-TRICALCIUM PHOSPHATE

1. Product Description

β-tricalcium phosphate (β-TCP) is a kind of substitute material for bone, which has good biodegradability, biocompatibility and bone induction ability. It can form a close combination with bone. It is non-toxic, non-stimulating, non-allergic, non-mutagenic, non-hemolytic, non-destructive to biological tissue, and can form a strong chemical combination with bone. It is widely used for bone defect filling in plastic surgery. The product specifications meet the requirements of GMP standard of the medicine of China, YY/T 0683-2008 β-Tricalcium Phosphate for Surgical Implants.

2. Physicochemical Properties
Chemical name: β-tricalcium phosphate
Molecular weight: 310.18
Molecular formula: β-Ca3(PO4)2
Density: 3.14g/cm3
Ca/P  :1.5
Melting point: 1670 ℃
Element content: purity ≥ 99%, heavy metal ≤ 4 ppm, arsenic ≤ 1 ppm
Average Size: 300nm~20μm in various specifications
Morphology: amorphous form, sphericity
Cytotoxicity test: relative survival rate of 100% extract group ≥ 95%

3. Application Range

This product can be used to make β-TCP bioceramics, coatings and composite materials. After sterilization, it can also be used for plastic and cosmetic surgery, dental surgery, repairing bone defects and bone fusion caused by trauma, tumors, inflammation, bone diseases, etc. This product can be mixed with other bioceramic materials, such as HA, CSI and other powders to make composite bioceramic scaffolds with different compositions by 3D printing.



III. BIOMEDICAL GRADE CALCIUM SILICATE CaSiO3

1. Product Description

Calcium silicate (CSI) is a biologically active inorganic material with the ability to deposit hydroxyapatite-like substances. Among them, the element silicon is considered as a mediator to promote the formation of new bone. The degraded products are alkaline and are usually used to repair bone defects.

2. Physicochemical Properties

Chemical name: calcium silicate

Molecular weight: 116.1617

Molecular formula: CaSiO3

Density: 2.9 g/cm3

Melting point: 1540℃

Element content: purity ≥ 99%, heavy metal ≤ 4 ppm, arsenic ≤ 1 ppm

Average Size: 5μm

Morphology: needle-like form, rod-like form

Cytotoxicity test: relative survival rate of 100% extract group ≥ 95%

3. Application Range

This product can be used to make CSI bioceramics, coatings and composite materials. After sterilization, it can also be used for plastic and cosmetic surgery, dental surgery, repairing bone defects and bone fusion caused by trauma, tumors, inflammation, bone diseases, etc. This product can be mixed with other bioceramic materials, such as HA, β-TCP and other powders to make composite bioceramic scaffolds with different compositions by 3D printing. 

   


IV. BIOMEDICAL GRADE BOVINE BONE POWDER

1. Product Description

Bovine bone powder has good biocompatibility and is similar to mineralized human bone in morphology and chemical structure. As one of the bone graft materials, xenogeneic bovine bone powder has been widely used in clinic and has achieved good osteogenic effect.

2. Physicochemical Properties
Chemical name: bovine bone powder 
Element content: heavy metal ≤ 4 ppm, arsenic ≤ 1 ppm
Average Size: 1~20μm
Morphology: amorphous form
Cytotoxicity test: relative survival rate of 100% extract group ≥ 95%.
3. Application Range
  This product can be used to make bovine bone powder bioceramics, coatings and composite materials. After sterilization, it can also be used for plastic and cosmetic surgery, dental surgery, repairing bone defects and bone fusion caused by trauma, tumors, inflammation, bone diseases, etc. This product can be mixed with other bioceramic materials, such as HA, CSI and other powders to make composite bioceramic scaffolds with different compositions by 3D printing.



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